Ann & Robert H. Lurie Children's Hospital of Chicago provides superior pediatric care in a setting that offers the latest benefits and innovations in medical technology, research and family-friendly design. As the largest pediatric provider in the region with a 140-year legacy of excellence, kids and their families are at the center of all we do. Ann & Robert H. Lurie Children's Hospital of Chicago is ranked in all 10 specialties by the U.S. News & World Report.
Location
Job Description
The Research Scientist will perform lab work in the Immune Deviation & Disease Neighborhood. The lab investigates the role of mast cells and fibroblasts in driving inflammation and scarring in Eosinophilic Esophagitis (EoE).The candidate should be highly motivated with experience working in a translational/basic science laboratory setting using wet lab tools to define biological mechanism ideally associated with mucosal inflammation, allergic inflammation, or fibrosis. The Research Scientist should have considerable experience in all aspects of laboratory immunology and molecular biology research. Design, optimization and execution of experiments aligned with the lab mission and through reading literature is vital.
Proficiency in murine skills required: breeding, handling, oral gavage, intraperitoneal administration, cardiac puncture, topical (skin) application, and dissection. Proficiency in spectral flow cytometry is required including use of BD machines (e.g. FACS Symphony A3/A5/S6), high-parameter spectral panel design, troubleshooting, optimization of antibody dilution and gating using FMOs, sorting, and FlowJo analysis. The candidate should be willing to learn new machines (e.g. BD FACS Discover S8, BD FACS Symphony A5). The candidate should be able to work with research technician to complete experiments. The candidate should be proficient in RNA/DNA/protein isolation, RT-PCR, western blot/ELISA, immunohistochemistry/immunofluorescence, and cell culture including suspension and/or adherent human/murine cells. The candidate should be willing to new techniques (e.g. Crispr, air liquid interface, organoids). The candidate should have a strong ability to troubleshoot and collaborate with faculty members in the performance and analysis of complex research studies and acquisition of new skills.
The candidate should be able to coordinate with 1) core facilities, 2) clinical research coordinator and 3) research technician. The candidate should be able to complete mathematical calculations, computer tasks, & assist in judging the validity of data. The candidate should be able to follow protocols, policies, procedures, regulations, good clinical & laboratory practices. Manuscript writing is critical, and the candidate should have interest in grant writing. The candidate will maintain an agenda, lab notebook and project-based PowerPoints which will be presented at lab meeting and seminars.
Essential Job Functions:
Education and Experience:
Education
Master's Degree (Required)Benefit Statement
For full time and part time employees who work 20 or more hours per week we offer a generous benefits package that includes:
Medical, dental and vision insurance
Employer paid group term life and disability
Employer contribution toward Health Savings Account
Flexible Spending Accounts
Paid Time Off (PTO), Paid Holidays and Paid Parental Leave
403(b) with a 5% employer match
Various voluntary benefits:
Supplemental Life, AD&D and Disability
Critical Illness, Accident and Hospital Indemnity coverage
Tuition assistance
Student loan servicing and support
Adoption benefits
Backup Childcare and Eldercare
Employee Assistance Program, and other specialized behavioral health services and resources for employees and family members
Discount on services at Lurie Children's facilities
Discount purchasing program
There's a Place for You with Us
At Lurie Children's we embrace and celebrate diversity and equity in a serious way. We are committed to building a team with a variety of backgrounds, skills, and viewpoints - recognizing that diverse identities strengthen our workplace and the care we can provide to the Chicago community and beyond. We treat everyone fairly, appreciate differences, and make meaningful connections that foster belonging and allyship. This is a place where you can be your best, so we can give our best to the patients and families who trust us with their care.
Lurie Children's and its affiliatesare equal employment opportunity employers. We value diversity and are committed to creating an inclusive environment for all employees. All qualified applicants will receive consideration for employment without regard to race, color, sex, sexual orientation, gender identity or expression, religion, national origin, ancestry, age, disability, marital status, pregnancy, protected veteran status, order of protection status, protected genetic information, or any other characteristic protected by law.
Support email: candidatesupport@luriechildrens.org